Spider-Man 4: Sinister Six – Teaser Trailer (2025)

Marvel today unveiled a completely redesigned Sinister Six lineup that would fit in flawlessly with the MCU, giving Spider-Man’s most awesome adversaries a significant makeover. In Marvel continuity, the Sinister Six have appeared in numerous guises, with different villains banding together, generally under Doctor Octopus’s direction, to assassinate Spider-Man in situations where they have failed to do so on their own. Marvel’s new Ultimate Universe narrative is currently twisting the design in a way that is genuinely unexpected.

In solicit information for Ultimate Spider-Man #9, Marvel has revealed the introduction of a new Sinister Six. Assembled by Wilson FIsk’s Kingpin, this new team has some shocking members. And while Marco Checchetto’s art depicts the team standing mysteriously in the shadows, Marvel has revealed the designs for each villain, giving fans an in-depth look at the roster.